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By Vallet-regi M., M. Vila

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P. Pham, F. Liang, K. Wu, W. Edward Billups, L. J. Wilson and A. G. Mikos: Biomaterials Vol. 28 (2007), p. 4078 [26] I. Armentano, M. Dottori, D. Puglia and J. M. Kenny: J. Mater. Sci. Mater. Med. Vol. 19 (2008), p. 2377 [27] Y. H. Meng, C. Y. Tang, C. P. Tsui and D. Z. Chen: J. Mater. Sci. Mater. Med. Vol. 19 (2008), p. 75 [28] X. F. Shi, J. L. Hudson, P. P. Spicer, J. M. Tour, R. Krishnamoorti and A. G. Mikos: Biomacromolecules Vol. 7 (2006), p. 2237 [29] X. Shi, B. Sitharaman, Q. P. Pham, P.

76] investigated PLLA/HA/MWCNT electrospun composite membranes for the guided regeneration of complex multi-tissue structures at soft-hard tissue interfaces, as found in dental anatomy (periodontium) for example. The incorporation of HA or MWCNTs/HA nanoparticles was found to slow down the degradation of PLLA. It was hypothesised that the dissolving alkaline HA particles act as a physical barrier, which blocks the entry of water in the polymer backbone. This observation implies that degradation characteristics of polylactides can not only be controlled by the addition of CNTs (see §2) but also by HA particles.

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